Menthol, the cooling agent in peppermint, is added to almost all commercially available cigarettes. Menthol stimulates olfactory sensations, and interacts with transient receptor potential melastatin 8 (TRPM8) ion channels in cold-sensitive sensory neurons, and transient receptor potential ankyrin 1 (TRPA1), an irritant-sensing channel. It is highly controversial whether menthol in cigarette smoke exerts pharmacological actions affecting smoking behavior. Using plethysmography, we investigated the effects of menthol on the respiratory sensory irritation response in mice elicited by smoke irritants (acrolein, acetic acid, and cyclohexanone). Menthol, at a concentration (16 ppm) lower than in smoke of mentholated cigarettes, immediately abolished the irritation response to acrolein, an agonist of TRPA1, as did eucalyptol (460 ppm), another TRPM8 agonist. Menthol's effects were reversed by a TRPM8 antagonist, AMTB. Menthol's effects were not specific to acrolein, as menthol also attenuated irritation responses to acetic acid, and cyclohexanone, an agonist of the capsaicin receptor, TRPV1. Menthol was efficiently absorbed in the respiratory tract, reaching local concentrations sufficient for activation of sensory TRP channels. These experiments demonstrate that menthol and eucalyptol, through activation of TRPM8, act as potent counterirritants against a broad spectrum of smoke constituents. Through suppression of respiratory irritation, menthol may facilitate smoke inhalation and promote nicotine addiction and smoking-related morbidities.
It is a Vaseline like substance, with a strong smell of menthol. used commonly, to rub on the chest and put some under the nose of a person with a cold. menthol is said to help unstuck a stuffy nose.
Menthol will help clear your sinuses.
kareena kapoor
Menthol is... well, "menthol".
Since all cigarettes fall into the category of either menthol or non-menthol, the answer is yes.
Menthol cigarettes do.
There are no perfect rhymes for menthol.
Get something called a retainer : Its a clear nose ring . : )
Since each menthol isomer has 3 stereocenters, menthol has a total of 8 stereoisomers.
Longbeach Menthol is 8mg Longbeach Menthol Fresh (Lighter Green Packet) is 2mg
They clear your sinuses. They really make your nose run if you have a stuffy nose.
It is not safe to put menthol in the anus.