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"The corpus luteum synthesizes progesterone, estradiol, and 17-hydroxyprogesterone. The increased progesterone levels affect the thermoregulatory site in the hypothalamus and increase the core body temperature. Negative feedback from the increased release of estradiol and progesterone from the corpus luteum results in decreased serum LH and FSH levels in the luteal phase. If conception has not occurred, FSH levels increase again at the end of the luteal phase as the progesterone and estradiol levels decrease. The decrease in progesterone and estradiol levels results in shedding of the endometrium-i.e., menstruation. LH pulse frequency is high (90 minutes) and of low amplitude in the follicular phase. The pulse frequency and amplitude increase immediately before ovulation".

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Q: How does progesterone play a role in a feedback mechanism?
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