How does protein structure affect protein function?

Answer 1

The primary structure is simply a long chain of peptides (polypeptide chain). The peptide monomers are like letters in a long, long word (the polypeptide). The word, a product of the primary structure and the peptide bonding sequence means something - whether it be, "I'm a transport protein." or "I'm an enzyme!". So, the primary structure definitely dictates the function of a protein by the sequence of amino acids it has. The primary structure's sequence of amino acids also dictates how the polypeptide will form (its structure). The R-group on the amino acids, which varies, will cause an amino acid to be positive, negative, polar, or nonpolar. This will cause the peptide chain, after these amino acids have been put together through dehydration reactions, to attract/form bonds with each other differently, leading to specific structures based off of the primary structure of a protein. These bonds vary between hydrophobic interactions, van der Waals attractions, hydrogen bonds, disulfide bridges, and a couple of other bonds. These new bonds and formations result in the secondary and tertiary levels of structure

Answer 2

Primary structure is protein in its simplest form, as a long chain of amino acids. To have function, the polypeptide chain folds and bends and bonds form between itself and other molecules to make more complex structures. These more complex structures confer function.

Answer 3

Even a slight change in primary structure can affect a protein's conformation and ability to function.

1. The substitution of one amino acid (valine) for the normal one (glutamic acid) at a particular position in the primary structure of hemoglobin, the protein that carries oxygen in red blood cells, can cause sickle-cell disease, an inherited blood disorder.

2.The abnormal hemoglobins crystallize, deforming the red blood cells into a sickle shape and clogging capillaries

Answer 4

Primary structure of proteins is of very much important. There is unique sequence of amine acids denoted by sequence of codons coming from genes. If a single amine acid is short, then entire chain of amine acid will brake up. If a single amine acid is different, then body immune system will recognize it with time and will form antibodies against that protein. For example, in pig insulin one amine acid is different from human insulin, body will eventually form antibody against it, with time, making us to increase the dose of insulin with time passes by.

Answer 5

Absolutely. The sequences of amino acids that compose the primary structure can be incredibly long; however, there is no room for error. For example, sickle-cell disease in blood cells is caused by just one error in the primary structure, but has incredibly adverse effects on the organism.

Answer 6

yes by the change of its molecular bonding they could mostly be attempt to kill some one so it is shur to chek it and run a test for the I.P.D.