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Q: Why does the structure of a protein or enzyme determine its function?
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Which two levels of protein structure principally determine the active site of an enzyme?

Quaternary and Tertiary levels of protein structure principally determine the active site of an enzyme.


Is renin a hormone?

by function is enzyme ... by structure is hormone


Give an example of the relationship between structure and function?

One example of the relationship between structure and function is found in enzymes as their function is dependent upon its structure. Enzymes are catalytic proteins that speed up a reaction without being consumed. Their protein structure enables them to recognize their substrates, even among isomers, thus allowing them to catalyze very specific reactions. The interactions between a protein's primary structure, its amino acid sequence, determine its secondary structure of hydrogen bonded alpha and beta pleated sheets. The side chains of the amino acids help determine the next superimposed structure, the tertiary structure and the quaternary structure if the protein has one. A protein's conformation enables it to form an active site whose shape is compatible with that of the substrate. Once the substrate enters the active site, the enzyme's structure is altered as induced fit moves the active site's chemical groups into positions that enhance their ability to catalyze the chemical reaction, thus improving the enzyme's function. An enzyme's structure is so closely correlated to its function that even a slight change in a protein's primary structure can affect its conformation and ability to function. For example, although noncompetitive inhibitors bind to the enzyme away from its active site, they alter the enzyme's conformation so that the active site no longer has the right structure to bind with the substrates, preventing it from functioning correctly.


Which methods you can use to determine the primary structure of an enzyme?

Off the top of my head: techniques such as chemical and enzymatic degredation (particularly if they are targeted) coupled with various analytical techniques particularly mass spectrometry and NMR. X-ray crystallography could also be used if the enzyme can be crystallised.


What is the key feature of a protein or enzyme that makes its function correctly?

The most important feature that makes functional to a protein or an enzyme is its three dimensional structure based on its tertiary structure. Either, a structural protein, where alpha helices and beta sheets are vital to its function, or an enzyme, where the shape of its active site is crucial for its biological activity, the tertiary structure is the most important characteristic. In fact, the process called "protein folding" is one of the key biochemical areas of study for the scientific community.


What does enzymes functions depend on?

The function of an enzyme is dependent on the shape of the enzyme. The structure and shape determines what the enzyme can do.


When is a protein considered an enzyme?

When it has the potential to facilitate a chemical reaction; to make it faster. The structure of enzyme-proteins can accelerate a chemical reaction by bringing reactants together by its binding, confinement properties, among others. Structure can indeed easily code for function.


What determine an enzymes function and how many function does one enzyme have?

two


Does the shape of an enzyme protein determine specificity?

Shape of an enzyme specifically shape of its active site determines enzyme specificity .


What are the functions of enzyme linked receptors?

Most enzyme-linked receptors function as protein kinases.


Is an enzyme a structural protein or functional protein?

Yes, enzymes are proteins and it is their sequence of amino acids (primary structure) that determines what kind of an enzyme it is and makes all the enzymes unique and it is the tertiary structure of enzymes that maintains their shape and give rise to the unique active site. When an enzyme is denatured, it loses its tertiary structure and therefore its shape.


Why is an enzyme not a type of protein?

Actually it is. It is a polypeptide structure that has been specialized to be a catalyst.