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Shape of an enzyme specifically shape of its active site determines enzyme specificity .

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Q: Does the shape of an enzyme protein determine specificity?
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If an enzyme is a protein how might you change the specificity of such an enzyme?

What an enzyme does is based on its shape, therefore you would have to change it on a molecular level in order to alter its job.


How might an amino acid change at a site distant from the active site of the enzyme alter the enzyme's substrate specificity?

The alteration of an amino acid on a site other than the active site will: change the shape of the protein.


Can an enzyme bind to nearly any molecule?

No; enzymes have substrate specificity, which means the substrate has to be a specific shape for the enzyme to bind to it.


What determines the specificity of a protein?

The sequence of amino acids determines the specific function of a protein. The shape and structure of the protein determines where in the cell it can go.


How does DNA determine a protein's shape?

DNA determines a protein's shape by determining the sequence of the amino acids in a protein.


How amylase enzyme change on heating?

Most proteins including enzymes are very sensitive to heat. When heated it will break the bonds that give the protein its shape. The protein only functions because of its shape. So when we heat a protein/enzyme, it changes its shape and it no longer functions. This process is called denaturation.


Why is hair not an enzyme?

Hair like enzymes are made of protein. However for a protein to be an enzyme it must have a very specific tertiary structure (shape) and have an active site that has a complementary shape to part of its substrate molecule. ie the enzyme must fit with the thing that it breaks down The tertiary sructure of hair is not highly folded and does not have a complementary shape to a substrate molecule therefore it is not an enzyme


What determine an enzymes activity?

There are several things that determine an enzyme's activity. The main determinants include the structure of the enzyme, temperature, pH and so much more.


Can an enzyme work on different substrates?

No, because an enzyme is a protein. The function of each protein is determined by its shape. The protein is only that protein and can do its job only when it is in its specified shape. Since an enzyme is a protein, it has a specific shape that is made for one particular substrate.


Is an enzyme a structural protein or functional protein?

Yes, enzymes are proteins and it is their sequence of amino acids (primary structure) that determines what kind of an enzyme it is and makes all the enzymes unique and it is the tertiary structure of enzymes that maintains their shape and give rise to the unique active site. When an enzyme is denatured, it loses its tertiary structure and therefore its shape.


What determines the three dimensional shape of an enzyme?

The order of amino acids for each protein determines its final three-dimensional shape


How is the shape of a protein or enzyme determined?

The most common methods used for the determination of protein structure are X-ray crystallography or NMR spectroscopy.