Basically, sickle cell anemia means that some of the red blood cells of the person with the disease are not the right shape, instead of being bowl shaped, they are half moon shaped. This means that they can't carry oxygen around the body as well as a person without the condition. As the sickle cells are not only the wrong shape, but also quite rigid, they can block the blood capillaries, so that tissues in the body become starved of oxygen (ischemic). The blockages can vary loads in severity/frequency etc, and they can end up causing a stroke or heart attack if blocking a blood vessel to the brain or heart. One of the organs that is really badly affected by this is the spleen. It has really narrow blood vessels leading to it, so can get starved of oxygen badly and frequently. Normally this means that people with sickle cell anemia do not have a working spleen by the end of childhood, so are at risk of infections. People with sickle cell anemia tend to have more red blood cells than people without the condition as their body over compensates for the red blood cells.
Major pain in different parts of body
Sickle Cell Anemia affects all body parts as long as blood flows to that part and as long as it is prone to pain. Besides it is *anaemia not ammonia.
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natural selection and heredity Americans are affected with sickle cell anaemia which mostly affects black people.
Red blood cells.
Sickle cell anemia is a genetic blood disorder affecting individuals who inherit two copies of the abnormal hemoglobin gene from both parents. This primarily affects people of African, Mediterranean, Middle Eastern, and South Asian descent.
Since the capacity of the blood to carry oxygen is lower with sickle cell anaemia, your whole body is effected. You get tired very quickly, and because of the anormal shape of the blood cells strokes are more likely because coagulation can happen more easily.
The male female ratio is 1:1 since there is no sex predilection for Sickle Cell Anemia.
If both parents are carriers of the sickle cell trait (genotype AS), there is a 25% chance that their child will inherit the sickle cell disease (genotype SS). Each parent has one normal hemoglobin allele (A) and one sickle cell allele (S), which means the possible combinations for their child are AA, AS, and SS. Therefore, the probability of the child being affected by sickle cell disease is 25%. If both parents have sickle cell disease (genotype SS), then all children will also be affected (100%).
Sickle cell generally affects those of African origin, more specifically those whose parents are from areas where malaria is common
I have sickle cell and scapular necrosis occurred because the none in my joints became soft from the many crises I had. My teeth also was affected and severe decaying occurred. My dentist said it was because of the necrosis and sickle cell.
Some of the symptoms that come with sickle cell trait can include fever, as well as an acute form of cell degeneration that can happen throughout the body.