Through diffusion.
A molecule that is too large or charged would be unable to diffuse through a cell membrane.
Because it is a small molecule, water can diffuse through the cell membrane.
The molecule that requires energy to pass through the cell membrane is typically an ion or a large polar molecule, such as glucose, which moves against its concentration gradient. This process is known as active transport and involves the use of ATP or other energy sources to facilitate the movement of these substances through specific transport proteins in the membrane. Examples include sodium-potassium pumps and glucose transporters.
Molecule A is likely smaller and more hydrophobic, allowing it to pass through the cell membrane easily via simple diffusion. Molecule B may be larger, polar, or charged, requiring a transporter or channel for passage across the cell membrane.
Globular Proteins
A larger molecule or a polar molecule that cannot passively diffuse through the cell membrane would most likely be actively transported. Examples include glucose, ions (such as sodium and potassium), and amino acids.
Isobutane diffuses more easily into a cell because it is a small nonpolar molecule that can pass through the cell membrane via simple diffusion. Sodium (Na) is a charged ion and cannot easily pass through the hydrophobic interior of the cell membrane without the assistance of specific transport proteins.
Potassium enters the cell through potassium channels that open in response to changes in membrane potential. Sodium enters the cell through sodium-potassium pumps, which actively transport sodium ions against their concentration gradient.
The cell membrane contains phospholipids.
Large molecules can enter a cell through endocytosis, where the cell membrane folds around the molecule, forms a vesicle, and brings it into the cell. This process allows the cell to take in nutrients, signaling molecules, and other substances that are too large to pass through the membrane directly.
Both potassium and sodium ions can "leak" through the cell membrane due to diffusion.
Large molecules can enter cells through processes like endocytosis, where the cell membrane surrounds the molecule and engulfs it in a vesicle. This allows large molecules to be transported into the cell without crossing the lipid bilayer of the membrane.