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How does the lock and key model of enzymes action explain the highly specific way some enzymes select a substrate?
Wiki User
∙ 8y ago
This refers to the hypothesis proposed by Emil Fischer in 1894 but confirmed until the 20th century. Fischer proposed that the specificity of an enzyme (the lock) for its substrate (the key) arises from their geometrically complementary shapes. More specifically, the noncovalent forces through which substrates and other molecules bind to the enzyme are identical in character to the forces that dictate the conformations of the proteins themselves. Both involve van der Waals, electrostatic, hydrogen bonding, and hydrophobic interactions.
A substrate-binding site consists of an interaction or cleft on the surface of an enzyme molecule that is complementary in shape to the surface (geometrical complementarity). Molecules that differ in shape of functional group distribution from the substrate cannot productively bind to the enzyme; that is, they cannot form enzyme-substrate complexes that lead to the formation of products.
Wiki User
∙ 7y ago
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How do pH temperature and substrate availability affect the rate of action of enzymes?
All enzymes have optimal conditons, when it will work at its best. For example, if the temprature is too high the protein can become denatured. This is alos the case with Ph. Substrate level also affects enzyma activity because the more substartes there are, the more enxymes can bind to them.
The graph below shows how two different enzymes react with a substrate as the temperature increases. Based on the results what conclusion can be drawn about the action of the enzymes as?
Enzyme A becomes less effective earlier than enzyme B.
Is a substrate an enzyme?
NO. The enzyme acts on the substrate. The substrate is the chemical/compound being altered by the action of the enzyme. They are NOT the same.
How do chemical reactions occur at the relatively low temperature found within Cells?
They occur under the strict and highly specific action of Enzymes.
What is the reactions and the products of the reactions?
Question is to be edited. What isreactions.......Not reactions it has to be reactants.Reactants are those which come into reaction and products are those the outcome of such reaction.CH4 + 2 O2 gives CO2 + H2O CH4 , O2 are reactants. CO2 , H2O are products.
What is lock and key model?
in order to explain the mechanism of enzymes action a German chemist Emil fischer,in 184,proposed the lock and key model.According to this model both the enzymes and the substrate possess specific complementary geometric shapes that fit exactly into one another.This model explain enzyme specificity.
What is locking key model?
in order to explain the mechanism of enzymes action a German chemist Emil fischer,in 184,proposed the lock and key model.According to this model both the enzymes and the substrate possess specific complementary geometric shapes that fit exactly into one another.This model explain enzyme specificity.
Why are enzymes so specific in their actions?
The enzymes are so specific to their action because they have substrate binding site which has three dimensional configuration which binds to the complementarity three dimensional substrate molecule and hence the enzymes are specific in binding the site and their action In case if the structural configuration of the enzyme changes the substrate is unable to bind at that site and the reaction does not take place
The graph below shows how two different enzymes react with a substrate as the temperature increases. Based on the results what conclusion can be drawn about the action of the enzymes as?
Enzyme A becomes less effective earlier than enzyme B.
What are characteristics of enzymes?
they are efficient. their action is affected by the environment. they are specific.
What characteristic of enzymes?
they are efficient. their action is affected by the environment. they are specific.
What is the Mode of action of enzymes in terms of substrate complex?
These are the modes: 1. Lock and Key hypothesis 2. Induced Fit Hypothesis
The graph below shows how two different enzymes react with a substrate as the temperature increases. Based on the results what conclusion can be drawn about the action of the enzymes as the temperatur?
enzyme B stays effective at higher temperatures than enzymes A
What is the lock-and-key principle of enzyme action?
The lock is the enzyme and it's active site is where you put the key in. The key is like the substrate that comes and binds to the active site, or the key that fits into the lock.
Why do enzymes only work with the specific substrates?
Enzymes act only on a specific substrate due to the active site of the enzymes fits perfectly with the substrate. Like 2 puzzle pieces, they can only go together and not with anything else. Enzymes catalyze or help a reaction take place. They bind substrates and then help position them in order that the chemical reaction between these substrates can take place. If they bound things other than the substrates they would be much less efficient in catalyzing the reactions.
How do pH temperature and substrate availability affect the rate of action of enzymes?
All enzymes have optimal conditons, when it will work at its best. For example, if the temprature is too high the protein can become denatured. This is alos the case with Ph. Substrate level also affects enzyma activity because the more substartes there are, the more enxymes can bind to them.
Who does the substrate work on enzyme action?
The substrate is the molecule(s) that an enzyme works on
