about 45 minutes, but its an easy drive
it is about 50 miles from fort Myers airport to Marco island
23 miles
It is 47 miles according to Google Maps.
115k
95 miles taking this route:Take I-75 NORTH, from Fort Myers, to SR-64 WEST to BRADENTON at EXIT 220B.Take SR-64 WEST, thru Bradenton, across to Ana Marie Island.
The shortest distance is 140 miles.
5 hours
It is 127.58 miles from North Fort Myers to Clearwater according to MapQuest.
In a straight line, Orlando, Florida to Fort Myers, Florida would be about 135 miles.
128 miles
130 miles