Hypernatremia is treated with infusions of a solution of water containing 0.9% sodium chloride (0.9 grams NaCl/100 ml water), which is the normal concentration of sodium chloride in the blood plasma
Hypernatremia is especially dangerous for children and the elderly
Severe hypernatremia has a mortality rate of 40-60%
Hypernatremia can cause neurological damage due to shrinkage of brain cells
High serum sodium levels (hypernatremia ) occur at sodium concentrations over 145 mM
--> causes of hypernatremia --> increased serum osmolality --> water shifts from cell to plasma --> cells shrink ---> manifestation
Severe hypernatremia, with serum sodium above 152 mM, can result in seizures and death
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High serum sodium levels