0
Want this question answered?
Be notified when an answer is posted
Add your answer:
Earn +20 pts
What is the oldest age for a person to live with muscular dystrophy?
In most cases this is diagnosed by age five. In that case the child would need a wheelchair by about age 12. Most likely the child will start to have heart and lung issues by late teens or early twenties. My guess no longer than thirty.
How can two unaffected people have a child who has Duchenne muscular dystrophy?
This is exactly how DMD is transmitted: the defect resides on the X chromosome. Women have 2 X chromosomes, so even if one of the X chromosomes has the DMD trait, the other X chromsome does not and they never get DMD. This is why boys exclusively get Duchenne - they have only one X chromosome. So if a woman carries the Duchenne trait, there is a 50% chance that she will pass DMD to her male offspring. Similarly, there's a 50% chance that her daughters will become carriers like her.
What are common muscular dystrophy pains?
There are many types of muscular dystrophy and are usually defined by where the symptons starts. Normal signs are soreness in the larger muscle groups, muscle weakness or poor balance ability. It's important to seek medical advise if you notice any signs of muscles weakness - such as problems with your balance capacity - on yourself or your child.
Muscular dystrophy?
DefinitionDuchenne muscular dystrophy is an inherited disorder that involves rapidly worsening muscle weakness.Alternative NamesPseudohypertrophic muscular dystrophy; Muscular dystrophy - Duchenne typeCauses, incidence, and risk factorsDuchenne muscular dystrophy is a rapidly-worsening form of muscular dystrophy. Other muscular dystrophies (including Becker's muscular dystrophy) get worse much more slowly.Duchenne muscular dystrophy is caused by a defective gene for dystrophin (a protein in the muscles). However, it often occurs in people without a known family history of the condition.Because of the way the disease is inherited, males are more likely to develop symptoms than are women. The sons of females who are carriers of the disease (women with a defective gene but no symptoms themselves) each have a 50% chance of having the disease. The daughters each have a 50% chance of being carriers.Duchenne muscular dystrophy occurs in approximately 1 out of every 3,600 male infants. Because this is an inherited disorder, risks include a family history of Duchenne muscular dystrophy.SymptomsSymptoms usually appear before age 6 and may appear as early as infancy. They may include:FatigueMental retardation (possible, but does not worsen over time)Muscle weakness Begins in the legs and pelvis, but also occurs less severely in the arms, neck, and other areas of the bodyDifficulty with motor skills (running, hopping, jumping)Frequent fallsRapidly worsening weaknessProgressive difficulty walkingAbility to walk may be lost by age 12By age 10, the person may need braces for walking. By age 12, most patients are confined to a wheelchair.Signs and testsA complete nervous system (neurological), heart, lung, and muscle exam may show:Abnormal heart muscle (cardiomyopathy)Congestive heart failure or irregular heart rhythm (arrhythmias) -- rareDeformities of the chest and back (scoliosis)Enlarged calf muscles, which are eventually replaced by fat and connective tissue (pseudohypertrophy)Loss of muscle mass (wasting)Muscle contractures in the heels, legsMuscle deformitiesRespiratory disorders, including pneumonia and aspiration of food or fluid into the lungs (in late stages of the disease)Tests may include:Electromyography (EMG)Genetic testsMuscle biopsySerum CPKTreatmentThere is no known cure for Duchenne muscular dystrophy. Treatment aims to control symptoms to maximize quality of life. Gene therapy may become available in the future.Activity is encouraged. Inactivity (such as bedrest) can worsen the muscle disease. Physical therapy may be helpful to maintain muscle strength and function. Orthopedic appliances (such as braces and wheelchairs) may improve mobility and the ability to care for yourself.Support GroupsYou can ease the stress of illness by joining a support group where members share common experiences and problems. See muscular dystrophy - support group. The Muscular Dystrophy Association is an excellent source of information on this disease.Expectations (prognosis)Duchenne muscular dystrophy leads to quickly worsening disability. Death usually occurs by age 25, typically from lung disorders.ComplicationsCardiomyopathyCongestive heart failure (rare)DeformitiesHeart arrhythmias (rare)Mental impairment (varies, usually minimal)Permanent, progressive disability Decreased mobilityDecreased ability to care for selfPneumonia or other respiratory infectionsRespiratory failureCalling your health care providerCall your health care provider if:Your child has symptoms of Duchenne muscular dystrophySymptoms worsen, or new symptoms develop, particularly fever with cough or breathing difficultiesPreventionGenetic counseling is advised if there is a family history of the disorder. Duchenne muscular dystrophy can be detected with about 95% accuracy by genetic studies performed during pregnancy.ReferencesKliegman RM, Behrman RE, Jenson HB, Stanton BF. Muscular dystrophies. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa:Saunders Elsevier; 2007:chap 608.
How do you get life insurance for a son that has muscular dystrophy?
The biggest thing when determining whether a person with muscular dystrophy can obtain coverage is whether it is localized or not. If it is localized, they can usually obtain a traditional life insurance policy at a Table 2-6 range. If it is not localized it could mean a decline. It is often times more complicated if it is a child, but guarantee issue options are available. You would definitely want to work with an experienced high risk life insurance agency who has success with these types of cases.
If you married a man having myotonic dystrophy will your kids have it as well?
Myotonic Dystrophy is an autosomal dominant disorder, meaning that there is a 50 percent chance of having a child with the disease, when one of the parents has it. This particular condition tends to become worse with each successive generation.So, yes there is a 50% chance that your child will inherit the disease, and it is likely that they would have a worse case than your husband. The best thing you can do at this point is to consult a genetic counselor, who can help you to make the decision that is best for you.
Facioscapulohumeral muscular dystrophy?
DefinitionFacioscapulohumeral muscular dystrophy is progressive muscle weakness and loss of muscle tissue.See also: Muscular dystrophyAlternative NamesLandouzy-Dejerine muscular dystrophyCauses, incidence, and risk factorsFacioscapulohumeral muscular dystrophy affects the upper body, unlike Duchenne muscular dystrophy and Becker muscular dystrophy, which affect the lower body.Facioscapulohumeral muscular dystrophy is a genetic disorder. It appears in both men and women and may develop in a child if either parent carries the gene for the disorder.Facioscapulohumeral muscular dystrophy affects approximately 5 out of 100,000 people. It affects men and women equally.SymptomsFacioscapulohumeral muscular dystrophy mainly affects the face, shoulder, and upper arm muscles. However, it can affect muscles around the pelvis, hips, and lower leg.Symptoms often do not appear until age 10 - 26, but it is not uncommon for symptoms to appear much later. In some cases, symptoms never develop.Symptoms are usually mild and very slowly become worse. Facial muscle weakness is common, and may include:Eyelid droopingInability to whistleDecreased facial expressionDepressed or angry facial expressionDifficulty pronouncing wordsShoulder muscle weakness causes deformities such as pronounced shoulder blades (scapular winging) and sloping shoulders. The person has difficulty raising the arms because of shoulder and arm muscle weakness.Weakness of the lower legs is possible as the disorder gets worse. The weakness can be severe enough to interfere with walking.Hearing loss and abnormal heart rhythms may occur, but are rare.Signs and testsA physical examination reveals weakness of the facial and shoulder muscles. High blood pressure may be noted but is usually mild. An eye exam may show changes in the blood vessels in the back of the eye.Tests that may be done include:Creatine kinasetest (may be slightly high)Electrocardiogram (EKG)EMG(electromyography)Genetic testing of chromosome 4Hearing testMuscle biopsy(may confirm the diagnosis)TreatmentThere is no known cure for facioscapulohumeral muscular dystrophy. Treatments are given to control symptoms and improve the person's quality of life. Activity is encouraged. Inactivity such as bedrest can make the muscle disease worse. Physical therapy may help maintain muscle strength.Expectations (prognosis)Disability is often minor. Lifespan is usually not affected.ComplicationsDecreased mobilityDecreased ability to care for selfDeformities of the face and shouldersHearing lossVision loss (rare)Calling your health care providerCall for an appointment with your health care provider if symptoms of this condition develop.Genetic counseling is recommended for couples with a family history of this condition who wish to have children.ReferencesKliegman RM, Behrman RE, Jenson HB, Stanton BF. Muscular dystrophies. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 608.
What symptoms of congential muscular dystrophy begin in infancy?
marked by severe muscle weakness from birth, with infants displaying "floppiness" and very little voluntary movement. Nonetheless, a child with CMD may learn to walk, either with or without some assistive device, and live into young adulthood or beyond
What is Duchenne Muscular Dystrophy?
Duchenne muscular dystrophy (DMD) is a severe recessive X-linked form of muscular dystrophy characterized by rapid progression of muscle degeneration, eventually leading to loss of ambulation and death. This affliction affects one in 3500 males, making it the most prevalent of muscular dystrophies.A:A very simple explanation of Duchenne Muscular Dystrophy (DMD) Duchenne Muscular Dystrophy is an X chromosome-linked, inherited, progressive, muscle wasting disease, which affects approximately one out of 3,500 male children.For explaining the nature of Duchenne Muscular Dystrophy (DMD), we might start with the chromosomes.Chromosomes are specifically folded DNA molecules. We speak of chromosomes rather than DNA, because in this form the DNA molecules are visible under the microscope, therefore, distinguishable from each other.In normal circumstances we have 46 nuclear chromosomes. In certain conditions, such as cancer (for example in cancerous 'HeLa cells'), the number of chromosomes could be different. The 46 chromosomes include 2 sex chromosomes as well. We inherit 23 nuclear chromosomes (22 plus 1 sex chromosome) from each of our parent.Females have two X chromosomes (XX), males have one X and one Y (XY). They each contribute one to their child. Since the mother has two X-es, she passes down one X, therefore the father's chromosomes decides the child's sex.Duchenne muscular dystrophy arises from the mother's defective sex chromosome. The disease is a recessive trait, meaning only one of the mothers' two XX sex chromosomes is defective and the other X chromosome is able to compensate.For this reason, if she passes the disease-carrying chromosome to her daughter, the daughter's disease-free paternal X chromosome would compensate. The girl will carry, and potentially be able to pass, the faulty chromosome to her child/children, but, she, herself, will not be at all, or just mildly, affected.If, however, her son gets the disease-carrying chromosome, he will not have that opportunity; due to his Y chromosome from his father, he cannot compensate. Unfortunately, he will get the full-blown disease.While the majority of the disease are inherited from the mother, as detailed above, 'spontaneous mutations', when the damage to the gene happens in the male child, is also possible.So, what is the role of the X chromosome in that disease?The long DNA molecules, therefore their tightly packed forms, the chromosomes, have specific areas, called 'genes'. Every chromosome has its 'own' specific genes on their 'own' specific areas. Those genes have the 'blueprints', the instructions, for the body to build proteins. Proteins are compounds, specific substances, which are essential to life; they are vital for every function, feature, and aspects of the body.If a gene is faulty, inherited from either or both parents, (Duchenne muscular dystrophy is inherited only from the mother), or damaged/changed by environmental factors (like radiation, chemicals, or others), also by life style (smoking for example), then it cannot provide a correct instruction to assemble a properly working protein.The fault arise from mistakes in the instruction; some parts are missing, others are repeated, and some are changed. It is like someone is building a cupboard. If the instruction gives the wrong dimensions for some parts or even omit some others parts, then it would be impossible to build a proper cupboard.Neither can the body assemble the protein, called 'dystrophin', from the improper instruction given by the defective Dystrophin gene of the X-chromosome.Dystrophin is a muscle protein with mechanical and protective functions. It might involve in cell to cell communications, as well. Due to the lack of dystrophin protein the muscles became weaker, damage easily, and gradually break down, waste away.Symptoms (difficulty in sitting unaided, delayed start for walking, frequent stumbling and falling, difficulty in getting up, for example), could start to appear as early as one year of age, and the disease quickly progresses to the stage when the child needs a wheelchair (around 8-12 years of age).Since the disease weakens not only the skeletal muscles, but all muscles, heart rhythm and the pumping ability of the heart are also affected. Likewise, breathing becomes difficult and needs assistance as the disease progresses to those involved muscles.Lifespan, unfortunately, is not expected to extend beyond 30 years. Cure is not possible at the present.Treatments are aimed to delay the wastage, steroid medication (with Vitamin D and calcium supplement to counteract its possible bone weakening side-effect), physiotherapy, and water exercises, possibility of low frequency electrical muscle stimulation, among others.Improving the quality of the patients' life includes corrective bone surgery (bone deformities occurs frequently) to improve posture and comfort, braces, use of wheelchair (manual then electric), heart medications/treatments, assistance with breathing (ventilator, masks, others), - education/information/help to parents and carers, for example.Research is ongoing, internationally, on several possible aspects; a few examples are:· 'Gene bandage', specifically designed for the protein assembling process to 'skip over' the faulty segment of the gene, enabling the production of dystrophin,· Implantation of stem cells,· 'utrophin-based therapy', Utrophin is another muscle protein with similar function. Research going on to use it for compensate for the lack of dystrophin,· Researching a drug (recently trialled in Diabetes Type 2 research, as well), which, also, could increase the level of HSP72 (a specific protein). HSP72 expected to improve muscle function, decrease muscle break down, and increase lifespan by 20 %,· and an older research into low frequency electrical muscle stimulation.
Does having a child make you an adult?
Having a child when young does not make the girl an adult.
Can you stop having pierids when you have a child?
no u cant stop having periods if u have a child
If your child has a child does that emmancipate her?
In the US, no, having a child does not emancipate a minor.
