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Fluid retention is common in heart failure cases. A loop diuretic such as frusemide can cause massive diruesis which leads to a smaller blood volume. It can hence reduce pulmonary and peripheral edema. Since loop diruetics reduce the blood volume, the preload will also be reduced. This will lead to the workload of the failing heart being reduced.

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Q: How is a loop diruetic used to treat heart failure?
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