that's not true, in fact magnesium sulfate has been tested on rats and dogs, and it does have an ld50. "The LD50 values were 206 mg/kg for males and 174 mg/kg for females"
30000000 ng
LD50 relates to the compound/element, not to poisoning - it is the LD50 of mercury. It varies depending on route of exposure and the animal tested but it is around 1 to 15 mg/kg body-weight.
563 mg or about 0.8 milliliters.
The LD50/50 (50% mortality in 50 days) for strontium-90 in rats is estimated to be around 2.5 to 3 microcuries per gram of body mass. I do not know if that translates linearly to humans.
1530 mg per kilogram bodyweight, when taken orally by a rat (test on humans would be unwise).
YES they do. Its disgraceful.It depends on the test. Everyone complains about the Draize test, which is the one where they hold open rabbits' eyes and drip chemicals in them. The one that's worse is the LD50 test. This determines the "acute toxicity" of a substance--LD50 means the dose that kills half the animals who receive it. They can do a skin contact LD50, an oral LD50, an inhalation LD50 (more correctly LC50--inhaled chemicals are rated in parts per million in air) or an injection LD50. If you are doing an oral LD50 on antifreeze, you squirt a measured dose of antifreeze down the throats of 100 animals--anything from mice to dogs are used. You then count the number of animals that die over the next 14 days. At the end you euthanize the ones who are still alive. If 50 or more of the animals died from antifreeze, you record the dose as the LD50 and you're done. If fewer than 50 die, you repeat the test with a new batch of animals and a higher dose. Antifreeze kills by destroying the kidneys, and there are even worse chemicals than that--imagine having to run an inhalation LC50 on nerve gas!
In toxicology, the median lethal dose, of a toxin is the dose required to kill half the members of a tested population after a specified test duration. LD50 figures are frequently used as a general indicator of a substance's acute toxicity.
ld50 for lamotrigine
Hazard Class 6 contains poisonous materials (6.1) and infectious agents (6.2). Division 6.1: Poisonous material is a material, other than a gas, which is known to be so toxic to humans as to afford a hazard to health during transportation, or which, in the absence of adequate data on human toxicity:Is presumed to be toxic to humans because it falls within any one of the following categories when tested on laboratory animals (whenever possible, animal test data that has been reported in the chemical literature should be used):Oral Toxicity: A liquid with an LD50 for acute oral toxicity of not more than 500 mg/kg or a solid with an LD50 for acute oral toxicity of not more than 200 mg/kg.Dermal Toxicity. A material with an LD50 for acute dermal toxicity of not more than 1000 mg/kg.Inhalation Toxicity: A dust or mist with an LC50 for acute toxicity on inhalation of not more than 10 mg/L; or a material with a saturated vapor concentration in air at 20 °C (68 °F) of more than one-fifth of the LC50 for acute toxicity on inhalation of vapors and with an LC50 for acute toxicity on inhalation of vapors of not more than 5000 ml/m³; or
Less.
15 years old
you can use analyze <regression <probit
thipental
The radiation LD50 of most insects is far higher than the LD50 of mammals.
LD50 (short for lethal dose 50) is the dose of a substance at which it kills 50% of test subjects.
that's not true, in fact magnesium sulfate has been tested on rats and dogs, and it does have an ld50. "The LD50 values were 206 mg/kg for males and 174 mg/kg for females"