How is sickle cell anemia iherited?

Answer 1

Recessively, that means that both parents must be symptomless carriers then there is only a 1 in 4 chance that a given child will be born with the disease.

Note: symptomless carriers have the strong advantage of being much more likely to survive malaria than "normals". Sickle cell disease is inherited through a single pair of genes (one gene from each parent), on chromosome 11. They must receive the gene from both parents in order to actually get sickle cell disease. If they receive one gene for sickle cell disease from one parent but a normal gene from another, they have "sickle cell trait." The genes that involve sickle cell control the production of hemoglobin (a protein) in red blood cells. Abnormal hemoglobin from sickle cell disease causes red blood cells to grow incorrectly.

Persons with sickle cell trait are much more resistant to malaria (a common disease in Africa, where the gene originated) than persons having two normal genes. This makes the sickle cell gene very likely to persist in areas where malaria is endemic, like Africa.

Answer 2

Sickle cell disease is inherited, which means it is passed from parent to child. To get sickle cell disease, a child has to inherit two sickle cell genes-one from each parent.

When a child inherits the gene from just one parent, that child has sickle cell trait. Having this trait means that you do not have the disease but you are a carrier and could pass the gene on to your children.

Answer 3

Sickle cell anemia is inherited when both parents pass the Hemoglobin S gene(trait) to their offspring. If only one parent has the Hemoglobin S trait then that child(ren) will only have the sickle cell anemia trait (such as myself) but will not have the sickle cell anemia disease. Now, if both parents have the Hemoglobin S trait then that child will have Sickle cell anemia. Basically both parents have to have the Hemoglobin S trait (Sickle cell anemia TRAIT) for their child to get it. So, if I were too have a child with someone who has sickle cell anemia trait then our child will have sickle cell anemia disease. *The trait does not mean you have the disease it just mean you are a carrier for sickle cell anemia

Answer 4

It is autosomal recessive, meaning that you must get one copy of the gene from each parent.

If you get a single copy from one parent and a normal one from the other you have what we call "trait". You will not have any problems yourself but can pass it on to your children.

Answer 5

Hemophilia is a sex-linked autosomal recessive genetic disorder.

Sickle-cell disease is an autosomal recessive disorder where heterzygotes benefit in regions where malaria is endemic and homozygous recessive individuals are profoundly affected by abnormally shaped red blood cells.

Answer 6

Both are genetic Down syndrome is most usually caused by the woman being over the age of 35 at the time of conception therefore an amniocentesis is strongly recommended.

Answer 7

yes; it's a genetic disorder.