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Setting directions means that a business establishes milestones that help them achieve their overall goals. As the business meets objectives, it moves in one direction.
North Carolina
The process of setting the overall appearance of the text within the document.
overall location and time period
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format
The setting is North Carolina. It seems that every book he writes that the setting is North Carolina. He must be "attached" or have some experience with this certain place.
The physical location, the place the story occurs in. In better stories the setting may be incorporated to perform more significant functions in supporting other aspects of the story. What those functions are can be many and varied.
Earthly place
medical staff
medical staff
The absence of people suggests that taking a walk at night is unusual.