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I have been on Wellbutrin and Lexapro for the past 4 years with no problems, however, I wanted to get off of the Lexapro because my life has changed and I felt I didn't need it anymore. My doctor said it was one of the easier drugs to get off of.......WRONG! I was told to go from 10mg a day to 5mg for 2 weeks then just quit. My first week off was ok, I had the occasional brain zap but the 2nd week was terrible. I had something like the flu (upset stomach, headache, could not sleep), plus the brain zaps constantly. I honestly couldn't deal with it anymore so I started snooping around on the internet and found several supplements that people were using - so I wrote them all down, went to the store and bought them all. I started taking them the next morning and, believe it or not, all of my symptoms went away...or were GREATLY reduced. Here is what I am taking: *Omega 3 fish oil soft-gels 1200mg, Bee Pollen 500mg, Folic Acid 800mcg, B-6 100mg, and Calcium Magnesium. I am not a health nut and usually don't take vitamins or supplements... Take them all first thing in the morning - one day I waited until lunch and had symptoms again. Good Luck! So far I have gone 5 days without any symptoms.

Every person is different so it could take a few weeks to a few months to have it totally out of your system. Drink plenty of water, exercise, keep busy, and if you feel yourself slipping back (you probably won't) please see your doctor.

If you have been on this medication for more than 3 months, please do not go off this medication without seeing your doctor. You should wean off this medication. Why? Because this medication alters the brain chemistry; don't put your body into shock. There can be some side effects if you do. Work with your doctor and slowly come off this medication.

One thing I should add in case anyone else reads this and wants to try 5-HTP - you should NOT take 5-HTP if you have taken any SSRI within the past two weeks. This can be potentially dangerous and lead to a condition called serotonin syndrome, where there is too much serotonin in your system. The SSRI works by preventing the serotonin from being reabsorbed by your nerve cells, and 5-HTP works because it is a chemical precursor to serotonin. Using both at the same time could result in way too much serotonin.

To answer more specifically about Lexapro, I think it must depend on how quickly your body can reestablish its own equilibrium with respect to serotonin. I slowly tapered down from 10mg/day of Lexapro and have not taken any at all for 18 days. I had none of the bad effects that lots of people describe, but I'm sure that is because I reduced my dose slowly. Oddly enough though, I have started experiencing waves of anxiety in the past few days, so I think Lexapro's "spell" can last quite a while, even weeks after completely eliminating it. I think I triggered this by drinking several beers over the past few nights. While on Lexapro I absolutely could not have any alcohol at all, they just majorly disagreed with each other. I thought after two weeks I'd be able to enjoy a few beers again, but I guess I was wrong.

I agree with you, anything that can affect you this much coming off of it is some potent stuff. I hope it loses its grip over me soon.

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Q: How long after going off Lexapro will you be yourself again?
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