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Shorter-acting BZPs take 15-20 minutes to work, whereas longer-acting BZPs can take up to an hour to reach therapeutic effect.

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Q: How long do benzodiazepines take to work?
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Can you take Phentermine and Ativan?

Absolutely. Phentermine and Ativan work on different neurotransmitters. Benzodiazepines create a calm effect by working through GABA. Phentermine, however, works on the neurotransmitters norepinephrine and dopamine. In fact, benzodiazepines are administered in cases of amphetamine overdose. However, a combination to avoid may be pain killers and phentermine, as they both work on the neurotransmitter dopamine. This may produce a "speedball" effect.


How long is Klonopin detectable in urine test?

Benzodiazepines can be detected up to a week after use.


How quickly is the therapeutic effect seen with benzodiazepines?

Usually fairly quickly, within a half an hour. Benzos are not used for long-term treatment. They are to fix anxiety right on the spot. Long-term medications are usually more like an SSRI antidepressant like Lexapro or Celexa. Those usually take about 3-4 weeks to work.