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Depends on from what temperature, to what temperature, the size of the mouse and for what purpose you're warming it.
If you are intending to feed it to a snake (or other reptile) from frozen, a pinky mouse should sit at room temp for a couple of hours or in a cup of slightly warm water for about half an hour. A full size mouse will take several hours at room temp and an hour or two in slightly warm water. I would recommend placing it in a plastic zip type baggy before you do either (definitely before you put it in water). Check the temp with your finger (on the outside of the bag, so the mouse doesn't smell like you) it should be right at room temp when you feed your snake.
Personally, I would always let them thaw either all day while I was at work, or overnight.
Never microwave your mouse or use hot water, this will cook the mouse which will provide less nutrients to your snake, and possibly make it not taste good to the snake (causing the snake to not eat or regurgitate it).
Also never feed your snake a cold mouse, since the snake is coldblooded it could make them sick.
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∙ 12y ago
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Up to 21 days
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