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It is impossible to drive to Lisbon from New York.
3 hours
3 seconds
21 hours
4.6 minutes.
45 minutes
24 hours
19 hours
It takes about 6 hours from Madrid to Lisbon and the distance is about 628 kms by car.
Suggest you Google Earth that one.
16 and 1/2 hours
2 and 1/2 hours