8 hours
It takes about 6 hours from Madrid to Lisbon and the distance is about 628 kms by car.
There are 388 miles from Lisbon to Madrid. It's a long 6 hour drive.
There is no high-speed train connecting Lisbon and Barcelona. The high-speed train from Barcelona to Madrid takes about 2hr and 40mins. The normal speed train from Madrid to Lisbon only leaves once a day and takes about 10hr to get from Madrid to Lisbon. It is a smarter idea to take the high-speed train to Madrid and transfer to a bus that will go to Lisbon.
2 hours and 15 minutes.
6 hours
27sec.27sec.
No.
Madrid and Lisbon
It will be between 1 and 2 hours by bus, depending on the number of stops. There are only 57 mules from Madrid to Segovia.
6:66
I don't think that is possible.