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A very high ratio of 1 in 11.

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How many African Americans are carriers of sickle-cell allele?

A very high ratio of 1 in 11.


What are the pros for SICKLE CELL ANEMIA?

The pro of sickle cell hemoglobin is that if you have only one allele for sickle cell hemoglobin and the other allele is normal, then you are immune to malaria.


What allele for the sickle cell trait is with the normal allele?

codominant


What is the allele for sickle cell trait with the normal allele?

codominant


How does the allele that causes sickle cell disease both help and harm people?

The allele that causes sickle cell disease provides a protective advantage against malaria, particularly in regions where the disease is endemic. Individuals who are carriers (heterozygous) for the sickle cell trait have some resistance to malaria, which can be life-saving. However, when a person inherits two copies of the sickle cell allele (homozygous), they develop sickle cell disease, leading to severe health complications, such as pain crises, organ damage, and reduced life expectancy. Thus, the allele's dual role illustrates a classic example of balanced polymorphism in human genetics.


The allele for the sickle cell trait is what with the normal allele?

The allele for the sickle cell trait is codominant with the normal allele. This means that in individuals with both alleles present, both traits are expressed.


If malaria were eliminated how might the frequency of the sickle-cell allele change over time?

Since people with the sickle cell allele trait are resistent to malaria, if malaria were eliminated there would be no change in the frequncy of sickle cell allele. This is because the presense of malaria does not have an affect on patients with the sickle cell allele trait.


What is the probability of am man and woman giving birth to a child who to is sickle cell like both of them?

If both parents are carriers of the sickle cell trait (genotype AS), there is a 25% chance that their child will inherit the sickle cell disease (genotype SS). Each parent has one normal hemoglobin allele (A) and one sickle cell allele (S), which means the possible combinations for their child are AA, AS, and SS. Therefore, the probability of the child being affected by sickle cell disease is 25%. If both parents have sickle cell disease (genotype SS), then all children will also be affected (100%).


For sickle-cell disease assume S is the dominant allele and s the recessive allele Which genotypes are possible for offspring of a carrier (Ss) and a person who lacks the sickle-cell allele (SS)?

SS,Ss


How does balancing selection affect the sickle cell allele in central Africa?

The sickle cell allele can be maintained in the central African population, above the frequency of gene mutation (balancing selection), because the heterozygous sickle cell individuals have an advantage in lifespan, in this malaria stricken region, over the homozygous alternatives. Homozygous sickle-sickle individuals die early from the sickle cell disease. Homozygous nonsickle-nonsickle die early from malaria. The heterozygous sickle-nonsickle have a higher survival against malaria and therefore the sickle cell allele is balanced selected.


Explain how 2 parents neither of whom have sickle cell could have a child with sickle cell?

Both were carriers.


Is there any genotype that is SC?

Yes, the genotype SC refers to individuals who have inherited one sickle cell allele (S) and one C allele, resulting in a sickle cell trait that is different from having sickle cell disease. This genotype can lead to some symptoms similar to sickle cell disease under certain conditions.