About 50 miles
The Keys are 120 miles long. Sanibel Island to Key West is 311 miles.
The distance between Key West in Florida to Sanibel Island in Florida is 132 miles. You would travel in a north west direction to get there.
about 150 miles
From the end of the Sanibel Causeway to Blind Pass, Sanibel Island stretches roughly 10.5 miles long.
The distance from Panama City Beach to Sanibel is 338 Miles.
67 miles
It is 230.05 miles according to MapQuest.
124 miles
108 miles
800 miles.
about 180 miles
The driving distance from Orlando to Sanibel Island is approximately 220 miles, which would take around 3.5-4 hours by car, depending on traffic and route taken.