800 miles.
The driving distance from Orlando, Florida to Sanibel is 188 miles.
The distance from Panama City Beach to Sanibel is 338 Miles.
The Keys are 120 miles long. Sanibel Island to Key West is 311 miles.
The driving distance is 163 miles.
The driving distance is 1,479 miles.
150 miles
about 43 miles
almost three hours
about 150 miles
“WHAT ARE RATES FOR SANIBEL ISLAND HOTELS ”
The distance between Key West in Florida to Sanibel Island in Florida is 132 miles. You would travel in a north west direction to get there.
It is 230.05 miles according to MapQuest.