about 150 miles
The distance from Panama City Beach to Sanibel is 338 Miles.
124 miles
almost three hours
The Keys are 120 miles long. Sanibel Island to Key West is 311 miles.
The distance between Key West in Florida to Sanibel Island in Florida is 132 miles. You would travel in a north west direction to get there.
The road distance between the places is 895 miles. This is the distance when the shortest route is chosen. Also it should be noted that various traffic rules like 'one ways' and 'no entries' have Not been considered when calculating this distance.
167.38 miles.
160 miles
The distance between the starting point and the destination is 231mi, (371.7 km), and will take approximately 4 hours of driving time.
The distance between the above mentioned places is 202.9 miles approximately. The distance is straight path from one place to another place. There might be slight difference between the actual distance and the above mentioned distance because of the route chosen.
200 road miles.
The closest town to midway between Sanibel Island, Florida and Hilton Head Island, South Carolina is Citra, Florida. The closest large town is Gainesville, Florida but it's a little way off the shortest route.