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Researchers kill between 1 and 1,300 animals may be killed for each cosmetic ingredient tested. Here are some common tests and the numbers of animals killed for each:

  1. Skin sensitization: 32 guinea pigs or 16 mice
  2. Skin irritation/corrosion: 1-3 rabbits
  3. Eye irritation/corrosion: 1-3 rabbits
  4. Acute oral toxicity: 7 rats
  5. Acute dermal toxicity: 20 rats, rabbits, or guinea pigs
  6. Acute inhalation toxicity: 20 rats
  7. Repeat dose (28 day) and subchronic (90 day) toxicity: 40 rats (28 day) or 80 rats (90 day)
  8. Carcinogenicity or combined carcinogenicity/chronic toxicity: 400 mice or rats
  9. Toxicokinetics: 4-12 rats
  10. Reproductive/developmental screen: 675 rats
  11. Reproductive toxicity in two generations: 2,600 rats
  12. Developmental toxicity: 480 rabbits (100 adult females and 480 pups) or 1,300 rats (100 adult females and 1,200 pups)
  13. Genotoxicity/mutagenicity: 12-500 mice or rats
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Q: How many animals are killed for one cosmetic?
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