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How many copies of the sickle cell allele do people with cycle cell disease inherit?
Wiki User
∙ 12y ago
To display symptoms it requires 2 copies. Someone with one copy would only be a carrier and not display any symptoms.
Wiki User
∙ 12y ago
Wiki User
∙ 14y ago2 copies
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Can achondroplasia be passed on to offspring?
Yes. Most cases of achondroplasia are associated with a dominant mutant form of the FGFR3 gene. Thus, if someone with achondroplasia has children with a person without achondroplasia, 50% of the offspring would be predicted to inherit the disorder. If two people with achondroplasia were to have children, 50% would inherit acondroplasia (i.e. would be heterozygous for the mutant FGFR3 allele), 25% would be normal, and 25% would inherit two copies of the mutant FGFR3 allele, a condition which is almost certainly lethal.
How do you find the possible genotypes of the children of a woman with blood type O and a man with blood type AB?
There are three alleles for blood type which can be represented by IA, IB, and i. A person with blood type O has the genotype ii. A person with blood type AB has genotype IAIB. If these two people produce children, those children will inherit one allele from each parent. They will therefore certainly inherit the i allele from their mother and either the IA or the IB from their father. The children with the genotype IAi will have type A blood, since the IA allele is dominant to the i allele. The children with the genotype IBi will have type B blood, since the IB allele is also dominant to the i allele.
Why is it that two normal parents could have a child with pku?
PKU, phenolketonuria, is a genetic disease caused by a recessive gene. So, a person with one normal and one faulty gene for this characteristic will not have the disease, you have to have two faulty genes to have the disease. If two people who each have one gene for PKU have a child, that child can inherit the gene from each parent and therefore will have two copies, causing the recessive trait to manifest.
What is a gene pool and how is it affected by natural selection?
A gene pool is the total number of genes of every individual in an interbreeding population. Which is like having every single gene of a population into one big pool (population).
What is the relationship between evolution allele frequency and population?
Consider an organism as a collection of inherited traits. Now consider each trait to be the expression of a single allele. An allele is a variant of a gene. For instance, if eye colour is coded for by a single gene, then there may be an allele A that codes for blue eyes, and an allele B that codes for brown eyes. A population gene pool, then, is the collection of all alleles present in a population of organisms from a single species. The allele frequency is the number of times a specific allele occurs in the population gene pool. For instance, the allele frequency of the brown-eye allele may be higher than the frequency of the blue-eye allele, meaning that more people have brown eyes than blue eyes, in this simplification.Evolution is measured in terms of changing allele frequencies. For instance, in our example, we could measure the number of people with blue eyes in generation one, and then measure the number again in generation one hundred. If we see a significant shift in frequency, then evolution has occurred.Nota bene: this is not how it works in reality, but it's easier to explain it in such simple terms than if I were to go into the complexities of population genetics.
When recessive gene for disease is inherited?
Recessive gene alleles are ones for which two copies are required to cause disease. Many people may have one copy and be phenotypically normal (non-diseased). People who have the disease will have gotten one copy from each parent, each of whom may be normal unless they, themselves have two copies.
How do people get Huntington's Disease?
HD is a genetic disease- you do not "catch it" from anyone. But is is inherited from a parent, just as you inherit hair color. One of the parents has a defective gene, which causes them to develop HD. If one of their children inherits that gene, they will also develop HD. However, if they do NOT inherit that gene, they cannot develop HD, and cannot pss it to their children.
How can the cycle of huntingtons disease stop?
People that MAY have Huntington's can have a genetic test- IF they are positive for HD, they may choose not to have children- and no one will inherit the gene that causes HD.
What is the name of the gene pair that consist of a dominant allele and recessive allele?
The name of the gene pair that consists of a dominant and recessive allele, i.e. (Xx) will be a heterozygous allele. In this situation, the characteristics of the dominant characteristic will mask that of the recessive allele. People have have a heterozygous genotype may be carriers for diseases that reside on the recessive allele.
How is sickle-cell disease a representation of codominance?
It's not sickle-cell itself, but rather being a heterozygous carrier of the disease. People with one dominant and one recessive allele for the disease are immune to malaria without the crippling effects of having sickle-cell anemia. I don't think that it can even represent codominance, though.
Is Cooley's Anemia found more commonly in certain groups of people?
The original term for cooley's anemia, is Mediterranean anemia. People from the Mediterranean origin tend to develop this disease more commonly. Children can inherit it from one of their parents.
Why are dominant alleles that cause lethal disorders less common that recessive alleles that cause lethal disorders?
A lethal dominant gene prohibits the organism from reproducing irregardless of the paired gene, so it is removed from the gene pool as soon as it appears. A lethal recessive gene, on the other hand, does not prevent reproduction unless it is paired with another lethal recessive, so it may be passed down through many generations before becoming paired and preventing reproduction.
