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I wish I knew the clear question here, but I am going to make a wild guess.

A female in season can and will be bred my any male allowed near her. She is not discriminating, it is possible for each pup to have a different father. In the Case of purebred dogs, if a bitch is accidentally bred by a male of a different breed, the resulting pups are mix breeds.

AT THE VERY NEXT SEASON, she may then be bred to her same breed and the resulting pups may then be deemed purebred.

The AMERICAN KENNEL club now allows breeding to multiple sires. There is a system in place to allow multiple sire breeding's to take place, the resulting offspring are then micro-chipped and each DNA tested and the DNA compared to the sires. Then each pup is registered to the individual sire. It is VERY EXPENSIVE to do this, but in the case of an older bitch , it is productive to breed a litter to multiple sires with the chance of improving the bloodline in different directions by one breeding, one pregnancy.

New Answer

1st Stage (proestrus) blood dripping and swelling of the vulva.

2nd Stage (estrus) blood turns to a light pink or straw colour, and the female will start mating behavior, she will also actively seek males.

3rd stage (diestrus) At this stage progesterone levels rise, whether the female was impregnated or not. The progesterone levels must be high in order for a female to remain pregnant.

4th Stage (Anestrus) time between heat cycles where progesterone levels are back to normal (Not in season).

A whole season will last for approximately three weeks, week coming in (1st Stage), week in (2nd Stage) and a week going out (3rd & 4th Stage). The blood only really looks pure at the beginning of her season, although it may darken slightly then go light watery pink in the last part of the season, but all dogs are different.

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Q: How many heat cycles does a dog go through before its blood is pure?
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