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Depending on where in Cincinnati to where in Nashville and on traffic in Louisville, anywhere from 4 to 5½ hours. In most cases from the Ohio River to downtown Nashville via I71 south to I-65 south the trip will take just a hair under 4½ hours. Taking I-265 or 264 around Louisville may be a good idea during Rush hour. It may be a little longer in distance, but it will be a little faster. Of course check construction and traffic conditions first!

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13y ago

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