There are far to many variables to accurately answer this question. 1st being, where in Colorado to where in Tennessee. 2nd, what type of routes are you going to be using? (Interstates, State Routes, or County Roads, etc.). 3rd, how often do you need to stop (Fuel, Food, Restroom, etc.). 4th, what are your driving habits? (do you drive the speed limit, speed, drive slow, etc.). So, as you can see, there is absolutely no way to accurately answer this one. Best suggestion would be instead of asking something like this on a site like this, wasting peoples time, next time you need an answer for something like this just use Mapquest, Google maps, Yahoo maps, or any of the other FREE online routing sites. (Or are you so INCREDIBLY LAZY as to not want to do your own research)
approx. 3 hours
It is a nine hour drive.
15 hours
Call it a 12 hour drive.
About 4 hours and 45 minutes.
They share a common border.
about 4 to5 hours
7 hours
Around 26 hours.
The Denver in Colorado is 26 hours from the Philadelphia in Pennsylvania.
I'm sorry, did you mean Manhattan, Kansas, and then COLORADO SPRINGS?
It takes about 3 and a half hours from the border.