Aprox. 6 hours 52 minutes.
6 to 7 hours
Google Maps estimates the driving time as 6 hours and 12 minutes.
Take I-70 WEST from Columbus to I-65 NORTH to CHICAGO via I-465 NORTH (EXIT 90 off I-70 in Indiana) and I-865 WEST (EXIT 25 off I-465).Take I-65 NORTH to Chicago.
Well, it has tolls and with traffic it would take 6 hours and 3 minutes.
Google Maps estimates the driving time as 6 hours and 11.
About 357 miles by car.
53 minutes
I - 95 does not go to Columbus, OH. You will have to take another route.
The shortest driving distance is 325 miles.
Take U.S. 33 SOUTH to ATHENS.
Just take I-70 EAST to Zanesville.
Take I-65 SOUTH from Indiana to I-465 EAST via I-865 (EXIT 129 off I-65).Take I-465 EAST around Indianapolis to I-70 EAST to DAYTON at EXIT 44.Take I-70 EAST to Columbus.