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Distance between Jacksonville, FL and Charleston, SC: According to Mapquest: 238.65 miles, estimated 3 hours 59 minutes driving time. According to Google Maps: 238 mi., estimated 4 hr. 1 min. driving time. Distance between Jacksonville, FL and Charleston, WV: According to Mapquest: 646.90 mi., estimated 10 hr. 6 min. driving time. According to Google Maps: 647 mi., estimated 9 hr. 55 min.. driving time

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Q: How many miles between Jacksonville and Charleston?
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