385 miles taking this route:
To get from Orlando Florida to Charleston South Carolina, it would take 6 hours and 16 minutes.
132 miles
212 miles
120 miles
195 miles
239 miles
It is 380.83 miles according to MapQuest.
127 miles
It is 174 miles from Sanibel, Florida to Orlando, Florida if you travel via US-17 North.
Orlando, FL is 110.7 square miles.
It is in San Agustin, Florida 105 miles from Orlando.
The Keys are 120 miles long. Orlando to Key West is 393 miles.