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385 miles taking this route:

  1. Take U.S. 17 SOUTH from Charleston to I-95 SOUTH to SAVANNAH.
  2. Take I-95 SOUTH to I-4 WEST to ORLANDO off EXIT 260B in Daytona Beach, Florida.
  3. Take I-4 WEST to Orlando.
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Q: How many miles from Charleston SC to Orlando Florida?
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