126 miles
It is 295.64 miles according to MapQuest.
1351
The Keys are 100 miles long. Key Largo is about 340 miles from Palm Coast. Key West is 440 miles.
about 1300 miles; between 20 and 21 hours
The distance between the start point and the destination is 426 miles, and will take approximately 7 hours 28 minutes of driving time.
289 miles taking this route:Take Florida's TURNPIKE (toll) SOUTH, from Orlando, to U.S. 1 SOUTH to KEY WEST at where Florida's TURNPIKE - ENDS in Homestead.Take U.S. 1 SOUTH to Key Largo.
Venice to Key Largo is 243 miles. Venice to Key West is 358 miles. Your exact distance is probably somewhere in there.
6.9 miles
2,422 miles
It is 63.12 miles according to MapQuest.
The driving distance is about 180 miles.