40% of the victims died
In the 20th century alone between 500 and 800 million people died of smallpox. That is why smallpox was eliminated.
1/3 of people died each year in the 16th century.
He was born in the 15th century and died in the 16th century.
An estimated 300 million people or more died from smallpox in the 20th century.
In the 16th century many people died in epidemics of sweating sickness (possibly influenza). Many others died of smallpox. (Queen Elizabeth I almost died of it. However she was given the most advanced medical treatment for smallpox -she was wrapped in red cloth.) Even if you survived smallpox it could leave you disfigured with pox marks or blind. Syphilis was also rampant. Dysentery was also a killer and many women died in childbirth (usually because of infection). Also the plague was very common.
Lots of people.
He died in the year 1506 - the 16th century.
Arrival of Spanish conquistadors during the 16th century. This is known as the "Mexican population collapse" whereas indigenous people died of smallpox and other European-brought diseases, falling from 20-40 million in the 15th century down to just 3-4 million by 1629.
He died 28 January, 1547. That would be the 16th century.
He lived in the 16th century, born 1540, died 1596.
16th Born 1491 Died 1547
i believe it causes multiple organ failure