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During the industrial revolution most died of illness from lack of hygiene. One of the most feared disease was the King Cholera but also typhoid and typhus were devastating. London is thought 7000 people died of the disease in the 1831-32 outbreaks which represented a 50% Death Rate of those who caught it. 15,000 people died in London in the 1848-49 outbreaks but the greatest killer in the cities was tuberculosis followed by Cholera which was given a chance to spread and 30,000 Londoners got the disease in 1849 with 15,000 dying as a result. Smallpox made a major re-occurrence in industrial cities even after Edward Jenner's vaccine because many in the industrial cities were ignorant of the fact that Jenner had developed a vaccine.

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