It is 259 miles via the shortest route according to Google Maps,
or you could take an easier (if only a bit longer) route (275 miles long) staying on the main roads taking this route:
232 miles
232 miles
-- To Palm Springs, California . . . 3,878 miles (rounded) -- To Palm Springs, Florida . . . . . 4,374 miles (rounded)
Which palm springs!?
The distance is 1,242 road miles to Palm Springs CA from Seattle.
Scottsdale to Palm Springs is a driving distance of 278 miles.
125 miles
The driving distance from Sedona, Arizona, to Palm Springs, California, is approximately 370 miles via I-10 W. The exact distance may vary depending on the specific route taken and any road conditions.
105 miles
14.2 miles
It is 445 miles between San Jose and Palm Springs.
There are about 268 road miles between Phoenix AZ and Palm Springs CA.