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Syphilis has 4 stages: primary, secondary, latent, and tertiary.

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Q: How many stages of infection are there in an incident of syphilis?
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Combating Syphilis: An Overview?

Syphilis is a common sexually transmitted disease caused by the bacteria Treponema pallidum. The main form of transmission occurs through sexual contact, though syphilis can also be transferred from the mother to the fetus during pregnancy and birth. Millions of people throughout the world today have contracted syphilis, with rates increasing dramatically within developing countries.Causes and ProgressionBecause syphilis is a sexually transmitted disease, it can be transferred through contact of broken skin and mucous membranes. Additionally, congenital syphilis occurs when a pregnant mother transmits the bacteria to the developing baby. The progression of syphilis can be documented in three stages. During the primary stage, painless sores develop at the site of initial infection, often disappearing in about five weeks. As the sores form, the bacteria collect within the body in an inactive form. In the secondary stage, untreated syphilis manifests in a variety of forms. Common symptoms include red rashes that spread over the body, and wart-like lesions within mucous membranes. It is important to realize that syphilis is extremely contagious during these first two stages. Finally, the tertiary stage is characterized when the bacterial infection spreads throughout the entire body. The bacteria can migrate to the nervous system, brain, heart, and skin. Extensive damage occurs to the points of bacterial migration; the tertiary stage occurs three years after the initial infection.SymptomsBecause syphilis progresses over many years, specific symptoms depend on the stage of syphilis. Common symptoms include painless sores, swollen lymph nodes, fever, rashes, and aches. Tertiary stage symptoms include problems to the heart, brain, and nervous system.TreatmentSyphilis can be effectively treated and cured if detected during the initial, early stages of infection. Antibiotics such as penicillin remain as the most effective treatment plan to combat syphilis. After initial treatment, blood tests must be conducted for the next two years to ensure the complete eradication of the syphilis bacteria. However, syphilis is very hard to treat when it reaches the tertiary stage. Further antibiotic treatment plans will limit further syphilis progression, but cannot undo the damage the bacteria have already done. Hence, late-stage syphilis may result in long-term health problems in numerous body systems. Constant therapy will be required to treat the body's long-term issues.


What does the acronym SVI stand for?

SVI is an acronym that stands for Secondary Virus Infection, which means that an infection could be at a different stage of life as a virus. Many times this is referred to as HIV stages in a person.


WhichSTDs can cause dementia or psychotic behavior if left untreated?

syphilis its has many stages starting from primary to tertiary at the tertiary stage it may affect the brain an spinal cord and may cause above mention condition.


Syphilis - tertiary?

DefinitionTertiary syphilis is a late phase of the sexually transmitted disease syphilis, caused by the spirochete Treponema pallidum.Alternative NamesLate syphilis; Tertiary syphilisCauses, incidence, and risk factorsSyphilis is a sexually transmitted, infectious disease caused by the spirochete Treponema pallidum.Syphilis has three main stages:Primary syphilisSecondary syphilisTertiary syphilisThis article focuses on tertiary syphilis. Tertiary syphilis can follow the initial infection (primary syphilis) by 3 to 15 years.In tertiary syphilis, the infection-causing organisms have continued to grow for years. Pockets of damage, or lesions, affects various tissues such as the bones, skin, nervous tissue, heart, and arteries. These areas are called gummas, and are very destructive.Tertiary syphilis is less frequently seen today than in the past because of early detection and adequate treatment.SymptomsSymptoms of tertiary syphilis depend on which organ systems have been affected. They vary widely and are difficult to diagnose. In individuals with tertiary syphilis, the primary and secondary stages of syphilis usually have been long forgotten. Medical findings of aortic aneurysms and neurological problems require astute diagnostic ability to link them to syphilis. Some of the symptomaticproblems are listed below.Cardiovascularsyphilis which affects the aorta and causes aneurysms or valve diseaseCentral nervous system disorders (neurosyphilis)Infiltrative tumors of skin, bones, or liver (gumma)Signs and testsVDRL or RPR blood tests are used as screening tests. If they are positive, one of the following is needed to confirm the diagnosis of syphilis:FTA-ABS (fluorescent treponemal antibody test)MHA-TPSpinal fluid examination in neurosyphilis shows signs of meningitis.TreatmentThe treatment of syphilis is determined by the length of time the person has been infected.Syphilis can be treated with antibiotics such as penicillin, G benzathine, doxycycline, or tetracycline (for patients who are allergic to penicillin). Length of treatment depends on the extent of the infection and factors such as the person's overall health.For treating syphilis during pregnancy, only penicillin is recommended. Tetracycline cannot be used because it is toxic to the fetus, and erythromycin may fail to prevent the spread of the infection (congenital syphilis) to the fetus. Penicillin-allergic individuals should be desensitized and then treated with penicillin.Several hours following treatment of early stages of syphilis, some individuals may undergo a febrile reaction called Jarisch-Herxheimer reaction. This is thought to be caused by the release into the circulation of material from dead or dying spirochetes. Symptoms of this reaction include:ChillsFeverGeneral feeling of being ill (malaise)Generalized joint aches (arthralgia)Generalized muscle aches (myalgia)HeadacheNauseaThese symptoms usually disappear within 24 hours.Follow-up blood tests must be done 3, 6, 12, and 24 months after treatment to ensure that the infection has been eliminated.Individuals with primary or secondary syphilis should abstain from sex until they have been treated. Syphilis is extremely contagious in the primary and secondary stages.Expectations (prognosis)Late syphilis may be permanently disabling and may lead to death.ComplicationsAneurysmsHeart valve diseaseNeurosyphilisSyphilis infection of the heartCalling your health care providerUntreated syphilis can result in serious health problems. It is very important that you tell your doctor if you think you might have had syphilis, even if it was many years ago.PreventionIf you are sexually active, practice safe sex and always use a condom.All pregnant women should be screen for syphilis.ReferencesCenters for Disease Control and Prevention (CDC). Recommendations and Reports: Sexually Transmitted Diseases. MMWR Morb Mortal Wkly Rep. 2006;55(RR-11).U.S. Preventive Services Task Force. Screening for Syphilis Infection: Recommendation Statement. Ann Fam Med. 2004;2:362-365.Hook EW III. Syphilis. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 340.Tremont EC. Treponema pallidum (Syphilis). In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 6th ed. Philadelphia, Pa: Churchill Livingstone Elsevier; 2005: chap 235.


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Syphilis?

DefinitionSyphilis is infection with the bacteria Treponema pallidum.Alternative NamesLues; Cupid's disease; SyphCauses, incidence, and risk factorsSyphilis is a sexually-transmitted infectious disease. The bacteria that cause it spread through broken skin or mucous membranes.Pregnant mothers infected with the disease can pass it to the baby developing in their womb. This is called congenital syphilis.Syphilis is widespread in the United States. It mainly affects sexually active adults ages 20 to 29.Syphilis has several stages.Primary syphilis is the first stage. Painless sores ( chancres) form at the site of infection about 2-3 weeks after you are first infected. You may not notice the sores or any symptoms, particularly if the sores are inside the rectum or cervix. The sores disappear in about 4-6 weeks, even without treatment. The bacteria become dormant (inactive) in your system at this stage. For more specific information about this type of syphilis, see primary syphilis.Secondary syphilis occurs about 2-8 weeks after the first sores form. About 33% of those who do not have their primary syphilis treated will develop this second stage. These symptoms will often also go away without treatment and again, the bacteria become dormant (inactive) in your system. For more specific information about this type of syphilis, see secondary syphilis.Tertiary syphilis is the final stage of syphilis. The infection spreads to the brain, nervous system, heart, skin, and bones. The dormant bacteria may be detectable either by seeing the damage they cause to a part of the body, or through a blood test for syphilis. For more specific information about this type of syphilis, see tertiary syphilis.SymptomsThe symptoms of syphilis depend on the stage of the disease. Many people do not have symptoms.In general, painless sores and swollen lymph nodes are possible symptoms of primary syphilis. Those with secondary syphilis may also have fever, fatigue, rash, aches and pains, and loss of appetite, among other symptoms. Tertiary syphilis causes heart, brain, and nervous system problems.For more information, see the article on the specific stage of syphilis.Signs and testsBlood tests can be done to detect substances produced by the bacteria that cause syphilis. The older test is the VDRL test. Other blood tests may include RPR and FTA-ABS.TreatmentAntibiotics are an effective treatment for syphilis. The antibiotic of choice is penicillin. The dose and how it's given (into a muscle or into a vein) depend on the stage of syphilis. Doxycycline may be used as an alternative treatment in individuals who are allergic to penicillin.Several hours after treatment of early stages of syphilis, you may have a reaction called Jarish-Herxheimer reaction. Symptoms of this reaction include:ChillsFeverGeneral feeling of being illGeneral joint achesGeneral muscle achesHeadacheNauseaRashThese symptoms usually disappear within 24 hours.You must have follow-up blood tests at 3, 6, 12, and 24 months to make sure the infection is gone. You should avoid sexual conduct until two follow-up tests show that the infection has been cured. Syphilis is extremely contagious through sexual contact in the primary and secondary stages.Syphilis is a reportable infection. That means that doctors must report any cases of syphilis to public health authorities, so that potentially infected sexual partners may be identified and treated.Expectations (prognosis)With prompt treatment and follow-up care, syphilis can be cured.Late-stage syphilis can lead to long-term health problems, despite therapy.ComplicationsComplications of untreated syphilis include:Damage to the skin and bonesHeart and blood vessel problems, including inflammation and aneurysms of the aortaNeurosyphilisCalling your health care providerNotify your health care provider if you develop signs or symptoms of syphilis. Several conditions may have similar symptoms, so you will need to have a complete medical exam.Also call your health care provider if you have had sexual contact with someone who has syphilis.PreventionIf you are sexually active, practice safe sex and always use condoms.All pregnant women, people with HIV, and others at increased risk for having syphilis should be screened for syphilis.ReferencesHook EW III. Syphilis. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier. 2007: chap 340.U.S. Preventive Services Task Force. Screening for Syphilis Infection: Recommendation Statement. Ann Fam Med 2004; 2: 362-365.


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