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Amphibolic pathways can serve either in energy-yielding catabolic or in energy requiring biosynthetic processes, depending on the cellular circumstances. For example, the citric acid cycle generates NADH and FADH2 when functioning catabolically. But it can also provide precursors for the synthesis of such products as glutamate and aspartate (from a-ketoglutarate and oxaloacetate, respectively), which in turn serve as precursors for other products, such as glutamine, proline, and asparagine

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Q: How the citric acid cycle serve as an amphibolic pathways?
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