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Usually by converting it to its sodium salt, by reaction with sodium hydroxide.

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Q: How will you change the aspirin to make it water soluble?
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What change is made to the structure of aspirin to make it soluble?

you replace the top hydrogen with a sodium ion so it becomes an ionic compound (or salt) :)


Why does aspirin dissolve in water?

Water is a polar molecule whereas aspirin has no overall charge so the two don't mix very well. Heating the water or adding a few drops of ethanol will make it dissolve a lot faster though. Correction: Aspirin (2-acetoxy-benzoic acid) is a moderately strong acid. It might be called a semi-polar molecule. Ethanol is similar in this respect, and is a good solvent for aspirin. As in all such cases, solubility is determined by the forces between the molecules in solid aspirin compared to the affinity between water and aspirin. The question has no trivial answer. The salts of weak organic acids are usually more soluble than the acids themselves. Adding a base such as sodium hydroxide or ammonia to the water is likely to bring more aspirin into solution - but strictly speaking, the dissolved specis is not 2-acetoxy-benzoic acid, but 2-acetoxy-benzoate.


Is hydrogen gas soluble in water?

slightly soluble, it will make water slightly acidic


Why does cold water make aspirin crystallize?

Aspirin dissolves in warm water. If cold water is used, that will give a maximum yield.


Is hydrogen sulfide gas soluble in water?

slightly soluble, it will make water slightly acidic


What makes iodine soluble in water?

You can make iodine soluble in water by addition of potassium iodide KI


Is glycerol soluble in water?

Glycerol is very soluble in water. This is due to the reason that glycerol has three hydrophilic hydroxyl grups in its structure which make it very soluble in water.


Compare the water soluble polyphenol content in various samples of tea leaves?

The soluble factor will change depending on the tea leaves that you use. the amount of the polyphenol will make a difference as well.


What make soluble in water will fizz when hydrochloric acid is added?

is soluble in water and will fizz when hydrochloric acid is added


How do you make quercetin water soluble?

methanol


How do you make sulfur water soluble?

Burning it makes sulfur dioxide which is water soluble, resulting in sulfurous acid solution.


Are monosacharides water soluble?

Monosaccharides are soluble in water because they contain hydroxyl groups and either a ketone or an aldehyde group. These polar functional groups make sugars very soluble in water.