that depends on person but your drug should be freely soluble in in that volume , literature says volume should be 2,3 or sometime 5 times the volume to soluble the drug in that much of volume.
A 900 ml dissolution medium is a common volume used in dissolution testing to ensure that there is an adequate volume for the drug to dissolve, without saturating the medium too quickly. This volume is also a practical amount that can fit into standard dissolution vessels and be easily mixed and sampled throughout the test.
Dissolution medium is a liquid used in dissolution testing to simulate the fluids of the gastrointestinal tract and assess the release of drug substances from pharmaceutical dosage forms. It typically contains various components such as electrolytes, buffers, and surfactants to mimic physiological conditions and ensure accurate measurement of drug dissolution rates.
The formula for dissolution calculation with media replacement typically involves determining the concentration of the solute in the dissolution medium over time. The general equation can be expressed as: [ \text{C}(t) = \frac{V_s}{V_t} \cdot \text{C}_s + \left(1 - \frac{V_s}{V_t}\right) \cdot \text{C}(t-Δt)] where (C(t)) is the concentration at time (t), (V_s) is the volume of the sample taken, (V_t) is the total volume of the medium, (C_s) is the concentration of the solute in the sample, and (C(t-Δt)) is the concentration at the previous time point. This formula accounts for the changes in concentration as media is replaced during the dissolution process.
The density of a medium is how much matter or mass there is in a given volume.
The volume of a medium-sized van can vary depending on the specific make and model. On average, a medium-sized van might have a cargo volume of around 120-150 cubic feet.
Ringtone on medium refers to the level of volume. It means that the ringtone is not at its loudest capability, but it is not as long as it could go. The ringtone volume is somewhere in the middle.
A low tone with a medium volume.
The density of a medium refers to it's mass per volume. This can also be defined as mass divided by volume. Pressure and temperature can change the density of a medium.
Dissolution is the process by which a drug substance dissolves in a liquid medium, such as gastric fluid, to become available for absorption. Disintegration, on the other hand, refers to the breaking apart of the tablet or capsule into smaller particles. Disintegration occurs first to increase the surface area for dissolution to happen efficiently.
The dissolution medium commonly used for testing Rabeprazole enteric-coated tablets is acidic buffer solutions such as Simulated Gastric Fluid (SGF) with a pH of 1.2 for the initial stage and then transitioning to Simulated Intestinal Fluid (SIF) at pH 6.8 to simulate conditions in the stomach and intestines, respectively. These buffers help to mimic the pH conditions the tablet will encounter in the gastrointestinal tract and assess its release characteristics.
Volume of irregular or regular shape object is the space reserved by the object in any medium.
I think they come in small, medium, and large.