All I know is that acetylcholine is the only neurotransmitter that transmits signals from nerves to skeletal muscles, so anything that blocks it would probably have the effect of you wanting to move your muscles, but either not being able to, or moving weakly.
Just a (educated) guess.
It would cause spastic paralysis (muscles are contracted and unable to relax)
Without the release of acetlycholine muscle could not contract.
Acetylcholine release is necessary for skeletal muscle contraction, because it serves as the first step in the process, enabling the subsequent cross-bridge formation. A muscle's ability to contract depends on the formation of cross-bridges between myosin & actin filaments. A drug that blocks acetylcholine release would interfere with this cross-bridge formation and prevent muscle contraction
The blocking of GABA release will cause convulsions, where as the blocking of acetylcholine will cause paralysis.
Acetylcholine release is necessary for skeletal muscle contraction, because it serves as the first step in the process, enabling the subsequent cross-bridge formation. A muscle's ability to contract depends on the formation of cross-bridges between myosin & actin filaments. A drug that blocks acetylcholine release would interfere with this cross-bridge formation and prevent muscle contraction
Botulinus toxin blocks the release of acetylcholine from the presynaptic terminal. This is a total blockage of neuronal transmission.
Atropine does not only block nicotinic receptors but also acetylcholine at muscarinic receptors
One of the main problems in Alzheimers disease is a decrease in acetylcholine, a neurotransmittor. Aricept blocks an enzyme called acetylcholine esterase from breaking down acetylcholine so that the available neurotransmittor can work for a longer period of time.
Acetylcholine Inhibitors...That would include organophosphates, curare (or tubocuranine), succinylcholine, (a flaccid paralytic used in anesthesia to relax striated muscles for intubation), and various neurotoxins.
There are many. The enzymes that can be affected are choline acetyltransferase (for making acetylcholine), and acetylcholinesterase (for breaking down acetylcholine). The most commonly used enzyme inhibitors affecting the cholinergic system are the acetylcholinesterase inhibitors, such as physostigmine, or neostigmine, etc.
It blocks the nicotinic cholinergic receptors on the muscle that normally bind the acetylcholine released by the motor neuron.
Aricept (donepezil) works by increasing levels of a neurotransmitter called acetylcholine in the brain, which helps improve memory and cognitive function in individuals with Alzheimer's disease. In Alzheimer's, there is a deficiency of acetylcholine, and Aricept helps to temporarily boost its levels to support cognitive function.
Atropine is a cholinergic antagonist which blocks the acetylcholine receptor causing increased sympathetic tone increasing the heart rate
it is an alpha-toxin that binds to acetylcholine binding sites on the postsynaptic cell membrane, which prevents the acetylcholine from acting. Curare blocks synaptic transmission by preventing neural impulses to flow from neuron to neuron. It does allow the action potential to travel in the axon, it just doesn't pass it on to the dendrite.