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Im not a doctor, but i think youll be fine taking tramadol. Tramadol is not an antibiotic. Tramadol is a stripped down piperadine molecule; a codeine analog. Tramadol has a weak affinity for the mu opioid receptor, and serotonergic properties similar to venlafaxine. If you are allergic to venlafaxine(effexor) or any synthetic opioid analgesics, then id be cautious about taking tramadol. Tramadol is usually used as a painkiller. I dont see any reason why a penicillin allergy would cause you to react badly to tramadol. they are two completely different drugs.

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Q: If allergic tp penicillin can you take tramadol?
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