Some gametes may have an extra copy of some genes.
Mistakes such as nondisjunction can occur during meiosis. This is the result of chromosomes failing to separate equally during either anaphase.
Nondisjunction occurs during anaphase, usually when referring to meiosis, when a tetrad fails to separate.
When chromosome pairs fail to separate aneuploidy occurs due to non-disjunction. This can result in monosomy or trisomy of the chromosome. These are mistakes made in chromosome segregation during meiosis. If pairs of homologous chromosomes fail to separate during the first meiotic division or if the centromere joining sister chromatids fails to separate during the second meiotic division, gametes, and hence offspring, will be produced that have too many and too few chromosomes.If this occurs in a cell of the body that is undergoing mitosis, the body will destroy the cell. If it occurs in a gametic cell (ovum or sperm) then the result can be trisomy, which is when the offspring receives three of the same chromosome rather than the normal two. Often the embryo will abort itself if this occurs but if you end up with three copies of chromosome 21 this is known as down syndrome. One the creation of a cell with trisomy, another cell results that is missing the chromsome so it is possible to end up with gametes missing a chromosome aswell, which will usuallr cause the embryo to abort, or may lead to serious defects in the offspringThe tetrads (pairs of homologous chomosomes) split up during Anaphase I in Meiosis I.
During meiosis, genetic recombination of homologous chromosomes occurs. So meiosis does result in genetic variation. After prophase I, during which crossing over occurs, every chromosome will have some maternal DNA and some paternal DNA.
Nondisjunction
It is the failure of chromosome pairs to separate properly during cell division.
Nondisjunction occurs in too many cells or too few cells causing defects
homologous chromosomes fail to separate during meiosis
Nondisjunction occurs when homologous chromosomes do not seperate. -Amber ^-^
Down syndrome (trisomy 21) occurs when a gamete carrying an extra copy of chromosome 21 is involved in a fertilization event.The gamete (whether sperm or oocyte) has an extra copy of chromosome 21 because of something called NONDISJUNCTION. This happens when a chromosome gets pulled to the wrong daughter cell.This can happen either in meiosis I or meiosis II.If nondisjunction happens in meiosis I, 2 gametes will be n+1 (have the extra copy of 21) and the other 2 gametes will be n-1 (will have NO copy of 21)If nondisjunction happens in meiosis II, 2 gametes will be normal, one will be n+1 and one will be n-1.
If nondisjunction occurs, abnormal numbers of chromosomes may find their way into gametes, and a disorder of chromosome numbers may result.
if nondisjunction occurs in meiosis 1 then the resultant sperms are XY carrying sperm n sperm without sex chromosome............ if XY carrying sperm fertilizes with normal X carrying ovum it results in XXY abnormal zygote if sperm without sex chromosome fertilizes with normal X carrying ovum it results in XO abnormal zygote
Autosomal nondisjunction is the most prolific cause of trisomy 21, or down syndrome, a defect that usually occurs during meiosis 1, but can occur during 2 as well.
If nondisjunction occurs during meiosis the result could be a wide range of mutations. Most likely it would result in mosaicism meaning there will be a mixture of affected cells and non affected cells.
Mistakes such as nondisjunction can occur during meiosis. This is the result of chromosomes failing to separate equally during either anaphase.
Crossing over occurs during Prophase I of meiosis.
Nondisjunction occurs during anaphase, usually when referring to meiosis, when a tetrad fails to separate.