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If food has harmful mould on it it may not be safe to eat even if the mould is killed. This is because some moulds leave residual toxins. The same applies to bacteria.

Some moulds are not harmful in foods and are used to create those foods: such as in cheeses.

To kill moulds and most bacteria, food needs to be raised to a temperature above 60°C (145°F) for at least two minutes. Note that this is the temperature the food needs to reach. The middle of a thick dense piece of food will take some time to reach the temperature of the oven.

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Q: If there is mold in bread crumbs and you then cook it in the oven do you cook off some of the bacteria?
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