the last person to answer this queston is a jerk...it depends on what fuse. there are main engine fuses under the hood that could prevent the car from starting...these are the ones that dont look like fuses you can buy at Walmart...they are quite large and high amperage.
Main fuse.
If the car is a Diesel there is 30 amp open fuse on the firewall
It depends what fuse but yes it is possible. If it is the ignition fuse then yeah your car won't start. If it is the fuse for your horn, yeah the car will still start.
your car wont start!
THEY MAY ALL BE ON THE SAME FUSE, CHECK THE FUSE BOX FOR A BLOWN FUSE
I found out that I had a blown ignition fuse.
Blown fuse.
You know your car has blown a fuse if whatever the fuse is for suddenly quits working. For example if your radio is playing and for no reason quits it may be a fuse has blown.
Blown fuse
Replace blown fuse
Not while it is in the fuse holder. Pull it out and if you cannot look and tell if it is blown or not, test it with an Ohm meter.
If replacing the main fuse does not make the repair, it is likely another fuse is also blown. Sometimes fuses will blow all along a circuit.