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Oxygen is used to metabolize carbohydrates and produces carbon dioxide. In addition an increased rate of respiration will lower carbon dioxide levels while increasing oxygen concentrations to saturation. Despite this they are two independent parameters. If someone were to be at a high altitude they could have almost no C02 in their blood, be breathing rapidly and have low oxygen levels. Similarly carbon monoxide will bind strongly to hemoglobin so that oxygen levels will go down, but since except at very low levels of oxygen, breathing will remain unchanged as CO2 levels, which drive the rate of respiration normally will be unchanged.

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Q: If you have raised CO2 in the body does that mean your oxygen saturations would be lower and work of breathing would increase?
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