up and east
Southeast
West
North
You would travel south southeast.
It depends on where in the US you are flying from. If you are flying from Detroit you would fly in a SSE direction. From Miami you would go ESE.
Mostly north.
South!
It depends where you live.
East
Yes, you can travel from the US to Dover, England. Doing so would require a combination of air and ground (car, bus, or train) transportation.
east.
South southeast.