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organ transplantation
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∙ 9y ago
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What drugs are heart transplant recipients given?
Heart transplant recipients are given immunosuppressive drugs to prevent the body from rejecting the new heart.
Why are immunosuppressive drugs given to organ transplant recipients?
Permanently post-transplant. i.e forever. (for 99.9% of cases. There's always a few exceptions, e.g for identical twins).
What are the most common risks of heart transplantation?
The most common and dangerous complications of heart transplant surgery are organ rejection and infection. Immunosuppressive drugs are given to prevent rejection of the heart.
What organ contains the drug to reduce the risk of rejection that are given to organ transplant?
It is not an organ which contains the immunosuppressive drugs used to prevent rejection - the drugs are manufactured in a laboratory, in the same manner that something as simple as Paracetamol would be manufactured. These drugs can then be given to the transplant recipient orally (including via a nasal-gastric tube) or via an IV drip.
What can be done to reduce the risk of organ rejection?
To prevent the patient from rejecting the donated organ, usually the drug Tacrolimus will be used to immunosuppress the patient. (Although sometimes it's Sirolimus). Steroids are also commonly used alongside the main immunosuppressant.
How are patients treated after heart transplantation?
Because the chance of rejection is highest during the first few months after the transplantation, recipients are usually given a combination of three or four immunosuppressive drugs in high doses during this time
Are organ transplants better fron an identical twin to the recipient?
They aren't necessarily better, but immunosuppressive drugs are not needed afterward - that's always a benefit.
Who gets iatrogenic KS?
Iatrogenic KS, is observed in kidney and liver transplant patients who take immunosuppressive drugs to prevent rejection of their organ transplant
What are the drug interactions associated with taking the Thunder God vine?
People taking immunosuppressive drugs such as prednisone should not use thunder god vine.
What drugs are used to treat graft-vs.-host disease?
Both the acute and the chronic disease are treated with cortisone-like drugs, immunosuppressive agents like cyclosporine, or with antibiotics and immune chemicals from donated blood
Why has the development of ideas and techniques involving transplants since 1800 led to present successful transplants?
Transplants between 1800 and 1950 were not very successful, this is because there was not things like tissue typing and immunosuppressive drugs available, these are important because tissue typing test that the tissue is compatible with the body it will be transplanted to, and immunosuppressive drugs destroy the immune system so that the antiboddies wont destroy the new organ.
What is immunosuppressive drug?
Immunosuppressive drugs, immunosuppressive agents, or immunosuppressants are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to:Prevent the rejection of transplanted organs and tissues (e.g., bone marrow, heart, kidney, liver)Treat autoimmune diseases or diseases that are most likely of autoimmune origin (e.g., rheumatoid arthritis, multiple sclerosis, myasthenia gravis, systemic lupus erythematosus, Crohn's disease, pemphigus, and ulcerative colitis).Treat some other non-autoimmune inflammatory diseases (e.g., long term allergic asthma control).These drugs are not without side-effects and risks. Because the majority of them act non-selectively, the immune system is less able to resist infections and the spread of malignant cells. There are also other side-effects, such as hypertension, dyslipidemia, hyperglycemia, peptic ulcers, liver, and kidney injury. The immunosuppressive drugs also interact with other medicines and affect their metabolism and action. Actual or suspected immunosuppressive agents can be evaluated in terms of their effects on lymphocyte subpopulations in tissues using immunohistochemistry.[1]
