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Solid substances obtained from EUDRAGIT® RL 100 or EUDRAGIT® RS 100. EUDRAGIT® RL PO (Type A) and EUDRAGIT® RS PO (Type B) are described in the monographs quoted above. EUDRAGIT® RL 100 / RL PO and EUDRAGIT® RS 100 / RS PO are copolymers of ethyl acrylate, methyl methacrylate and a low content of a methacrylic acid ester with quaternary ammonium groups (trimethylammonioethyl methacrylate chloride). The ammonium groups are present as salts and make the polymers permeable. The molar ratio of ethyl acrylate, methyl methacrylate and trimethylammonioethyl methacrylate is approx. 1:2:0.2 in EUDRAGIT RL and approx. 1:2:0.1 in EUDRAGIT RS.
Mark Eisei Sugamori has written: 'Viability of islets of Langerhans microencapsulated in eudragit RL 100 for a bioartificial endocrine pancreas'
] Description: Methacrylate-based coating materials with a variety of functional properties.Functionality Trade name Anionic polymer of methacrylic acid and methacrylates with a -COOH group Eudragit® L 100-55 - powder, spray dried L 30 D-55 which can be reconstituted for targeted delivery in the duodenum Eudragit® L 30 D-55 - aqueous dispersion, pH dependent polymer soluble above pH 5.5 for targeted delivery in the duodenumEudragit® L 100 - powder, pH dependent polymer soluble above pH 6.0 for targeted delivery in the jejunumEudragit® S 100 - powder, pH dependent polymer soluble above pH 7.0 for targeted delivery in the ileum.Eudragit® FS 30 D - aqueous dispersion, pH dependent polymer soluble above pH 7.0, requires no plasticizerCationic polymer with a dimethylaminoethyl ammonium group Eudragit E 100 - granules, pH dependent, soluble in gastric fluid up to 5.0, swellable and permeable above pH 5.0. Eudragit® E PO - powder form of E-100Copolymers of acrylate and methacrylates with quarternary ammonium group. Insoluble, High PermeabilityEudragit® RL 30D - aqueous dispersion, pH independent polymer for sustained release formulationsEudragit® RL PO - powder, pH independent polymer for matrix formulationsEudragit® RL 100 - granules, pH independentInsoluble, Low PermeabilityEudragit® RS 30D - aqueous dispersion, pH independent polymer for sustained release formulationsEudragit® RS PO - powder, pH independent polymer for matrix formulationsEudragit® RS 100 - granules, pH independentCopolymers of acrylate and methacrylates with quarternary ammonium group in combination with sodium carboxymethylcellulose Eudragit RD 100 - powder, pH independent for fast disintegrating films 2) Applications:Enteric Coatings Eudragit® L 100-55 or L 30 D-55 - delivery to the duodenum (pH > 5.0). Exact pH controlled drug release can be adjusted by a combination of polymers and coating thickness. Eudragit® L 100 - delivery to the jejunum (pH > 6.0).Eudragit® S 100 - delivery to the intestine (pH 6.0 to 7.5), site specific drug delivery can be achieved by combining with Eudragit® L types.Eudragit® FS 30 D - delivery to the colon (pH >7.0).Acryl-eze® --one step dry enteric coating system, soluble at pH 5.5Sustained Release Coatings Eudragit® RL and RS - release profile determined by the ratio of RL to RS polymers, and the film thickness applied. Taste Masking Eudragit® RD 100, pH independent, fast disintegrating film Eudragit® E 100 and EPO, pH dependent cationic polymer, soluble in gastric fluid up to pH 5.0, swellable and permeable above pH 5.0Rapidly disintegrating Films Eudragit® RD 100
RL stands for Road Luxery
Eudragit is a brand name for a type of polymer used in pharmaceutical formulations. It is often used as a coating for tablets to control drug release and improve stability. Eudragit polymers come in various types with different properties to suit the specific needs of a formulation.
Robert Lawerence Stine
Robert Lawerence Stine
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The melting point of Eudragit L100 is around 160-170°C, while the melting point of Eudragit S100 is higher, around 200-220°C. Both polymers are commonly used in pharmaceutical formulations for coating purposes.
R.L. Stine's full name is Robert Lawrence Stine.
he wrote the goosebumps series and has over 100 books writen
RL stands for Reduced Level in terms of elevation. It refers to the height of a point or feature above a chosen reference point, usually a specified datum or benchmark. RL is commonly used in surveying, construction, and engineering to describe vertical measurements.