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Eosinophils are one of five classes of white blood cells that circulate in the blood stream. They are inflammatory cells and are involved in regulating the body's response to parasites as well as allergic reactions.
Eusonophils and Basophils produce histamine.Also mast cells produce histamine.
Basophil
Mast Cells
Histamine is a chemical mediator. These are released by mammalian cells and effect their cells in their immediate vicinity. Histamines are released from white blood cells in the airways, they are released in response to injury or an allergen. They cause small arteries and arterioles to dilate and the permeability of capillaries to increase. They produce an inflammatory response where swelling, itching and redness occurs.Histamines are what causes allergic reactions in people. They can cause hives, itchy skin, runny or stuffy nose and watery eyes.
Dermatitis, which is inflammation and irritation of skin and can be caused by contact with allergens that cause cells to produce histamine in response, such as those in poison ivy. They also treat allergic reactions to internally taken allergens, such as foods and medicines, which also produce histamine release. Penicillin is an example of drugs that cause allergic skin reactions of rash and hives in many people. Most anti-itch drugs are antihistamines and some common prescription antihistamines are hydroxyzine and cortisone. Common over the counter medicines for skin reactions are non-prescription strength topical cortsisone creams and ointments, and Benadryl.
Basophils are circulating white blood cells that release histamine, but mast cells also do so.
histamine is produced by basophils and by mast cells found in nearby connective tissues. It is found in virtually all animal body cells.[
mast cell
Mast cells and EC (enterochromaffin) cells produce histamine, which stimulates the parietal cell to produce hydrochloric acid.
Delayed hypersensitivity reactions-- Allergic reactions mediated by T cells that occur hours to days after exposure
Anti-itch drugs are usually antihistamine medicines taken by mouth or used topically, or in extreme needs can be taken by injection or intravenously. They are available over the counter and by prescription. They work to block the histamine receptors on cells by binding to them so histamine can not. When histamine is released by your body and attaches to cells, it causes cells to release chemicals that produce sneezing, itching, and other allergic responses. Common over the counter anti-itch drugs are cortisone topical medicines and Benadryl.